Bangladesh JOURNAL of Child Health

Cystic Fibrosis – An Update


Cystic fibrosis (CF) is said to be the most common lethal inherited disease of the
white population. It affects the exocrine glands of body, primarily of the gastrointestinal
and respiratory system. CF is caused by one of a large numbers of mutations of the
gene for a protein called the cystic fibrosis transmembrane conductance regulator
(CFTR). This CFTR regulates chloride and sodium transport across epithelial
membranes. The main complications involve in the lungs, with damage to the small
and large airways by chronic and recurrent bacterial infections.

 

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