Aim of epilepsy management is to cure seizure and to maintain a good quality of life1. Quality of life is affected not only by the epileptic attacks but also by the adverse effect of the drug. This concern is more in case of developing brain of children1. However, due to many reasons, selection of antiepileptic drug is a challenging task. During selection of a drug, three important drug properties need to be considered: efficacy, tolerability and safety. In the recent past, better understanding of the epileptogenesis and mechanism of action of drugs & their toxicities have helped in the development of new generation antiepileptic drugs (AEDs) which are effective as well as safer & better tolerable than older AEDs. The new generation AEDs are either approved and used widely or on clinical trial1,2.The introduction