Bangladesh JOURNAL of Child Health

Cystic Fibrosis: A Deadly Disease and the Vast Majority are Unaware of It


Cystic Fibrosis (CF) is a life-limiting multisystem genetic disease inherited as an autosomal recessive trait, was first described as a clinically distinct entity in 1938 by Anderson. Initially, it was considered a rare and lethal disease of infancy.1 A major breakthrough in the history of CF occurred in 1989 when its gene was identified on chromosome 7 at position q31.2 and till now more than 2000 mutations have been identified, grouped into five main classes that affect protein function are associated with CF syndrome. 

 

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