Abstract Background: Dengue fever is a major public health problem in Bangladesh. Suspicion, attention, and early tests are necessary to identify concurrent illnesses with dengue. This study was assessed to find out the other infections associated with Dengue fever to minimize morbidity and mortality. Materials & Methods: Hospitalized patients with fever were initially selected. After clinical and laboratory evaluation, fever with dengue NS1 or IgM positive cases were included. Among the 175 dengue patients; during follow-up, some patients had a persistent high fever, cough, dysuria, appearance/deepening of jaundice,and other toxic features that could not correlate with dengue. Relevant investigations were done to find out the co-infections among them.